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This information on Molecular Farming patents has been given to MolecularFarming.com by the FAAR Biotechnology Group Inc. which provides industry, government, universities and legal counsel with expert advice, consultation and evaluation of biotechnology research, business opportunities and intellectual property matters.
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Molecular farming / pharming / biopharming - plant viral system and viral vector patents

Issued patents are differentiated from applications in that applications are italicized.

Ahlquist, P. G., French, R. C., US 5,466,788, Nov 14, 1995, Subgenomic promoter, Mycogen Plant Science

Ahlquist, P. G., French, R. C., US 5,500,360, Mar 19, 1996, RNA transformation vector, Mycogen Plant Sciences

Ahlquist, P. G., French, R. C., US 5,633,447, May 27, 1997, Plant tissue comprising a subgenomic promoter, Mycogen Plant Science

Ahlquist, P. G., French, R. C., US 5,670,353, Sept 23, 1997, Subgenomic promoter, Mycogen Plant Science

Ahlquist, P. G., French, R. C., US 5,846,795, Dec 8, 1998, RNA transformation vector, Mycogen Plant Sciences

Ahlquist, P. G., French, R. C., Sacher, R. F., US 5,602,242, Feb 11, 1997, Hybrid RNA virus, Mycogen Plant Science Inc, (viral)

Ahlquist, P. G., French, R. C., Sacher, R. F., US 5,627,060, May 6, 1997, Hybrid RNA virus, Mycogen Plant Science Inc, (viral)

Ahlquist, P. G., French, R. C., Sacher, R. F., US 5,804,439, Sept 8, 1998, Plasmid encoding hybrid RNA virus, Mycogen Plant Science Inc, (viral)

Arntzen, C. J., Lam, D, M-K., US 5,914,123, June 22, 1999, Vaccines expressed in plants, Prodigene Inc., (viral)

Arntzen, C. J., Lam, D, M-K., US 6,136,320, Oct 24, 2000, Vaccines expressed in plants, Prodigene Inc., (viral)


Baszczynski, C. L., Lyznik, L. A., Gordon-Kamm, W. J., Guan, X., US 6,300,545, Oct 9, 2001, Mobilization of viral genomes from T-DNA using site-specific recombination systems, Pioneer Hi-Breds Intl Inc, (Agro-viral system)

Carrington, J. C., Dolja, V. V., US 5,491,076, Feb 13, 1996, Expression of foreign genes using a replicating polyprotein producing virus vector, Texas A & M Univ

Chapman, S. N., Santa Cruz, S. P., Oparka, K. J., Wilson, T. M. A., US 6,232,099, May 15, 2001, Method of producing a chimeric protein, Scottish Crop Research Inst, (viral)

Donson, J., Dawson, W. O., Granthan, G. L., Turpen, T. H., Turpen, A. M., Garger, S. J., Grill, L. K., US 5,316,931, May 31, 1994, Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes, Biosource Genetics Corp.

Donson, J., Dawson, W. O., Granthan, G. L., Turpen, T. H., Turpen, A. M., Garger, S. J., Grill, L. K., US 5,589,367, Dec 31, 1996, Recombinant plant viral nucleic acids, Biosource Genetics Corp.

Donson, J., Dawson, W. O., Granthan, G. L., Turpen, T. H., Turpen, A. M., Garger, S. J., Grill, L. K., US 5,866,785, Feb 2, 1999, Recombinant plant viral nucleic acids, Biosource Technologies Inc.

Donson, J., Dawson, W. O., Granthan, G. L., Turpen, T. H., Turpen, A. M., Garger, S. J., Grill, L. K., US 5,889,190, Mar 30, 1999, Recombinant plant viral nucleic acids, Biosource Technologies Inc.

Fitchen, J. H., Beachy, R. N., US 5,955,647, Sept 21, 1999, Method for using tobacco mosaic virus to overproduce peptides and proteins, Scripps Research Inst, (virus)

Fitzmaurice, W. P., Pogue, G. P., Lindho, J. A., US 6,656,726, Dec 2, 2003, Viral expression vectors, Large Scale Biology, (altered movement protein)

Gleba, Y., Dorokov, Y., Ivanov, P., Atabekov, J., WO 0229068, pub April 11, 2002, Vector system for plants, Icon Genetics, (viral IRES system)

Hamamoto, H., Sugiyama, Y., Nakagawa, N., Hashida, E., Tsuchimoto, S., Nakanishi, N., Matsunaga, Y. Okada, Y., US 5,618,699, April 8, 1997, Plant virus vector, plasmid, process for expression of foreign gene and process for obtaining foreign gene product, Kanebo Ltd. (TMV coat protein), also WO9320217A1

Kimyuk, V., Benning, G., Gleba, Y., WO 02068664, pub Sept 6, 2002, Recombinant viral switches for the control of gene expression in plants, Icon Genetics

Kimyuk, V., Gleba, Y., Gils, M., Skulachev, M., Marillonnet, S., WO 02088369, pub Nov 7, 2002, Processes and vectors for amplification or expression of nucleic acid sequences of interest in plants, Icon Genetics, (replicon from two vectors)

Koprowski, H., Yusibov, V., Hooper, D. C., Modelska, A., US 6,042,832, Sept 10, 2002, Polypeptides fused with alfalfa mosiac virus or ilarvirus capsid, Thomas Jefferson Univ, (vaccine) listed there as well

Koprowski, H., Yusibov, V., Hooper, D. C., Modelska, A., US 6,448,070, Sept 10, 2002, Polypeptides fused with alfalfa mosiac virus or ilarvirus capsid, Thomas Jefferson Univ, (vaccine)

Kridl, J. C., Bruening, G., Knauf, V. C., US 5,589,379, Dec 31, 1996, Geminivirus-based gene expression system, Calgene Inc., (plant virus)

Kridl, J. C., Bruening, G., Knauf, V. C., US 5,650,303, July 22, 1997, Geminivirus-based gene expression system, Calgene Inc., (plant virus)

Lin, N-S., Hsu, Y-H., US 5,849,891, Dec 15, 1998, Satellite RNA from bamboo mosaic virus as a vector for foreign gene expression in plants, National Science Council (Taiwan)

Lindbo, J. A., Pogue, G. P., Turpen, T. H., US 6,300,133, Oct 9, 2001, RNA transformation vectors derived from an uncapped single-component RNA virus, Large Scale Biology Corp. ( viral system)

Lindbo, J. A., Pogue, G. P., Turpen, T. H., US 6,300,134, Oct 9, 2001, RNA transformation vectors derived from a single-component RNA virus and contain an intervening sequence between the cap and the 5' end, Large Scale Biology Corp. ( viral system)

Lomonossoff, G. P., US 5,958,422, Sept 28, 1999, Modified plant viruses as vectors of heterologous peptides, Axis Genetics Inc., also CA2170412.

Lomonossoff, G. P., Johnson, J. E., US 5,874,087, Feb 23, 1999, Modified plant viruses as vectors, Axis Genetics Inc/Purdue Research Found.

Lomonossoff, G. P., Johnson, J. E., US 6,110,466, Aug 29, 2000, Modified plant viruses as vectors, Axis Genetics Inc/Purdue Research Found.


Maiti, I. B., Dey, N., Shepard, R. J., US 6,420,547, July 16, 2002, Use of full length transcript (Flt) from mirabilis mosiac caulimovirus to express chimeric genes in plants, Univ of Kentucky, (caulimovirus)

Mason, H. S., Palmer, K. E., Hefferon, K. L., Mur, T. S., Arntzen, C., US 6,392,121, May 21, 2002, Gemini virus vectors for gene expression in plants, Boyce Thompson Inst, (virus)

Masuta, C., Takanami, Y., Koiwai, A., US 5,304,731, April 4, 1994, (expired), Vector, Japan Tobacco, (satellite virus vector)

Meulewaeter, F., Cornelissen, M., Van Aarssen, R., Soetaert, P., Gossele, V., US 5,994,526, Nov 30, 1999, Gene expression system, Plant Genetics Systems, (viral system)

Meulewaeter, F., Cornelissen, M., Van Aarssen, R., Soetaert, P., Gossele, V., US 6,294,711, Sept 25, 2001, Gene expression system, Plant Genetics Systems, (viral system)

Mori, M., Okuno, T., Furusawa, I., US 5,418,153, May 23, 1995, Process for production of exogenous gene or its product in plant cells, Nihon Nohyaku Co Ltd (virus system).

Mori, M., Okuno, T., Furusawa, I., US 5,824,856, Oct 20, 1998, Process for production of exogenous gene or its product in plant cells, Nihon Nohyaku Co Ltd (virus system).

Paszkowski, J., Lazar, G., Shinshi, H., Rauseo, I., Hohn, T., Potrykus, I., US 5,215,903, June 1, 1993, Process for the maintenance and proliferation of a defective non-infectious virus genomes in proliferating plant materials, Ciba-Geigy Corp., (virus system)

Ponz Ascaso, F., Torres Pascual, V., Sanchez Sanchez, F., Martinez Herrera, D., US 6,392,124, May 21, 2002, Infectious vectors and clones of plants derived from the turnip mosiac virus (TUMV), Inst Nacional de Investigacion Y Tecnologia Agraria Y Alimentaria, (turnip mosiac virus)

Slightom, J. L., US 5,162,601, Nov 10, 1992, Plant potyvirus expression vector with a gene for protease, UpJohn

Takahashi, T., Serizawa, N., Koishi, R., Kawashima, I., US 6,307,038, Oct 23, 2001, Expression systems utilizing autolyzing fusion proteins and a novel reducing polypeptide, Sankyo Company, Ltd. (clover yellow virus)

Turpen, T. H., US 5,811,653, Sept 22, 1998, Viral amplification of recombinant messenger RNA in transgenic plants, Biosource Technologies Inc.

Turpen, T. H., US 5,889,191, Mar 30, 1999, Viral amplification of recombinant messenger RNA in transgenic plants, Biosource Technologies Inc.

Turpen, T. H., US 5,965,794, Oct 12, 1999, Viral amplification of recombinant messenger RNA in transgenic plants, Biosource Technologies Inc.

Turpen, T. H., US 6,462,255, Oct 8, 2002, Viral amplification of recombinant messenger RNA in transgenic plants, Large Scale Biology Corp

Turpen, T. H., Garger, S. J., McCulloch, M. J., Cameron, T. I., Samonek-Potter, M. L., Holtz, B., US 6,284,875, Sept 4, 2001, Method for recovering proteins from the interstitial fluid of plant tissues, Large Scale Biology Corp. (protein recovery).

Turpen, T. H., Renl, S. J., Grill, L. K., US 5,977,438, Nov 2, 1999, Production of peptides in plants as viral coat protein fusions, Biosource Technologies Inc.

Turpen, T. H., Renl, S. J., Grill, L. K., US 6,660,500, Dec 9, 2003, Production of peptides in plants as viral coat protein fusions, Large Scale Biology.

Xia, Y., US 6,395,965, May 28, 2002, Plant containing a gene construct comprising a chlorella virus promoter and a lac operator, Restoragen Inc., (chlorella virus)

Yadav, N. S., US 6,077,992, June 20, 2000, Binary viral expression system in plants, du Pont, (viral system)

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